ON THE COVER
The essential kinetochore component CENP-C is critical in regulating centromere homeostasis. The image shows a multipolar spindle metaphase cell, a consequence when CENP-C is overexpressed. Mitotic spindles (cyan) attach to the chromosomes (grey) via the kinetochore (CENP-C in red).
https://www.life-science-alliance.org/content/8/4/e202402819