A representative structure of Myosin VI(1050-1131) (cyan and orange) in complex with Clathrin light chain alpha(46-61) (yellow).  The isoform-specific helix of Myosin VI is shown in orange. (PDB 6e5n) (Biancospino, Buel, Niño, et al., Nature Communications 10(1):4974, 2019.)