Yinling Hu, Ph.D.
- Center for Cancer Research
- National Cancer Institute
- Building 567, Room 252
- Frederick, MD 21702-1201
- 301-846-1478
- huy2@mail.nih.gov
RESEARCH SUMMARY
Dr. Hu's research focuses on understanding the physiological activities of IKKα in skin tumorigenesis and inflammation and in revealing the mechanisms by which IKKα regulates these functions by using genetic animal models, including IKKα conditional knockout, IKKα kinase inactive knockin and IKKα transgenic mice, as well as molecular biology approaches.
Areas of Expertise
Yinling Hu, Ph.D.
Research
The research interests of the Inflammation and Tumorigenesis Section are to understand the physiological activities of IKKα in skin tumorigenesis and inflammation and to reveal the mechanisms by which IKKα regulates these functions using genetic animal models, including IKKα conditional knockout, IKKα kinase inactive knockin and IKKα transgenic mice, as well as molecular biology approaches.
Publications
- Bibliography Link
- View Dr. Hu's Complete Bibliography at NCBI.
IKKα inactivation promotes Kras-initiated lung adenocarcinoma development through disrupting major redox regulatory pathways
Autoreactive T Cells and Chronic Fungal Infection Drive Esophageal Carcinogenesis
An IKKα-nucleophosmin axis utilizes inflammatory signaling to promote genome integrity
The pivotal role of IKKα in the development of spontaneous lung squamous cell carcinomas
IKKalpha is required to maintain skin homeostasis and prevent skin cancer
Biography
Yinling Hu, Ph.D.
Dr. Hu received her undergraduate degree from the Chinese Academy of Medical Science, Beijing, China and received her Ph.D. from the University of Melbourne, Australia. She was a postdoctoral fellow in Michael Karin's laboratory, University of California at San Diego from 1996 to 2001. Dr. Hu established her own laboratory in 2001 when she became an assistant professor at the Science Park Research Division, MD Anderson Cancer Center. In 2008 she became a principal investigator in the Cancer and Inflammation Program and was awarded tenure in 2016.
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