Job Description
The Pediatric Oncology Branch (POB), CCR, NCI, NIH invites applicants for a full-time Staff Scientist position. This position is for a highly motivated individual with expertise and focus on molecular and functional genetic studies using preclinical models of pediatric and adult benign and malignant solid tumors. The POB is a vibrant, multidisciplinary research community conducting innovative, high-impact bench-to-bedside research and close collaboration between physicians and scientists with a primary focus on pediatric and young adult cancers.
The successful candidate will have the primary responsibility of leading the preclinical program of POB, and in particular the Tumor Evolution and Genomics Section. Key responsibilities include (1) the design and conduct of in vitro molecular and functional genomic assays to discover oncogenic mechanisms and vulnerabilities in pediatric benign and malignant tumors; (2) design and conduct of drug screening efforts to discover new therapeutic agents and therapeutic combinations for the treatment of pediatric benign and malignant tumors; (3) design and conduct of in vivo preclinical testing of novel therapeutic regimens; (4) data analysis, summarization and presentation of generated laboratory data and (5) oversight, guidance, and training to collaborators, postdoctoral students and other students, and personnel in the analysis of sophisticated molecular and genomic studies and maintenance of general laboratory organization and regulatory compliance. In addition, the staff scientist will provide guidance and advice to investigators in POB and CCR on new preclinical projects including utilization of novel genetic and molecular techniques and analysis. The candidate will participate in preclinical and translational meetings, assist with the development of new preclinical studies, drug screening, data analysis, and data presentation. The candidate will be expected to represent the POB at national and international meetings and to independently prepare and publish manuscripts resulting from preclinical research projects.
Disclaimers: The position is subject to a background investigation. The NIH is dedicated to building a diverse community in its training and employment programs.
Qualifications and Job Details
Required and Preferred Skills
Successful candidates should have a strong track-record of publications demonstrating contributions to cancer biology, molecular mechanisms of cancer and preclinical drug development. Detailed knowledge of both human, and mouse preclinical models of pediatric cancer models is required. A high degree of ability to work independently on multiple projects and complete projects with acceptable timeline is required. Ability to work in a team and interact with scientists and clinicians in the intramural and extramural scientific communities. Previous hands-on experience discovering and optimizing small molecules for the treatment of cancer will be required. The individual will have strong logical/analytic thinking skills and expertise in working with multiple team members.
Candidates must possess a Ph.D., M.D., D.D.S, D.M.D., D.V.M. or equivalent degree in a biomedical, behavioral, or related science of have been certified by a university as meeting all the requirements leading to such a doctorate.
About the NCI Center for Cancer Research
The Center for Cancer Research (CCR) is home to nearly 250 basic and clinical research groups located on two campuses just outside of Washington, D.C. CCR is part of the National Cancer Institute (NCI) and makes up the largest component of the research effort at the National Institutes of Health (NIH). Centrally supported by long-term funding and a culture of complete intellectual freedom, CCR scientists are able to pursue the most important and challenging problems in cancer research. We collaborate with academic and commercial partners and advocacy groups across the world in efforts to prevent, diagnose and treat cancer and HIV/AIDS. The CCR research portfolio covers the full spectrum of biological and biomedical research. Our work ranges from basic to translational and clinical, and our clinical trials are conducted in the NIH Clinical Center, the world’s largest hospital dedicated to clinical research that offers a robust infrastructure to support CCR’s patients on an estimated 250 open studies. The success of CCR is grounded in an exceptionally strong discovery research program that provides the foundation for the seamless translation of insights from bench to bedside. Read more about CCR, the benefits of working at CCR and hear from our staff on their CCR experiences.
Bethesda
Bethesda is one of the most highly educated communities in the United States and has a nationally renowned school system. The city is a thriving suburban center close to Washington, D.C., and home to many restaurants, retailers and a flourishing arts and entertainment district.
Email a letter of interest, CV, and contact information for three references to Rebecca.shim@nih.gov. Reference letters will be requested upon invitation for an interview. Applications will be accepted until the position is filled.