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New insights show faulty immune cells are trained to become healthy

Researchers traditionally believed faulty T cells that have the potential to attack someone’s own tissues were eliminated before the cells leave the thymus. Now, research in mice shows that these autoreactive cells are evicted from the thymus and can mature into healthy cancer-fighting cells in the body’s peripheral tissues. This basic science discovery holds important implications for our understanding of autoimmune diseases and cancer.

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Center of Excellence In Chromosome Biology (CECB) Symposium

Date:  October 17-18, 2024
Location:  Natcher

The mission of the Center of Excellence in Chromosome Biology (CECB) is to achieve a comprehensive understanding of the mechanisms involved in chromosome function, how aberrations in chromosomes and chromatin lead to disease and how these defects can be corrected. Towards achieving our mission, this symposium brings together internationally renowned experts in the fields of chromosome structure and function with the focus on chromatin reprogramming during development, chromatin organization and dynamics, chromatin in cancer and aging and chromatin as a therapeutic target. This meeting will foster interaction among major laboratories in the areas of chromosome biology and enhance the education and development of junior investigators and follows in NIH laboratories studying chromosome biology in various diseases.

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Past, Present, and Future of Cellular Immunotherapy: Scientific Symposium Celebrating Steven A. Rosenberg's 50 years at NCI

Date:  September 26-27, 2024
Location:  Masur Auditorium, Building 10

The symposium will discuss the development of cell therapy for the treatment of human cancer, from early studies from the Center for Cancer Research's Surgery Branch to current clinical and translational research being performed around the world. Sessions will focus on the initial development of cell therapy for patients with metastatic melanoma, the introduction of gene engineering into cell therapy, and the use of cell therapy to address common epithelial cancers.  

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2024 NCI RNA Biology Initiative Workshop

Date:  April 23, 2024
Location:  NCI Shady Grove

The NCI RNA Biology Initiative aims to create an inter-disciplinary environment to facilitate the rapid exchange of information and expertise on the structure, function, and biological roles of RNA and to foster synergistic interactions amongst NCI investigators. We anticipate that insights into RNA biology and the development of RNA-based tools will define novel targets and accelerate the implementation of therapeutic interventions in cancer.

This one-day workshop will include internal and external speakers with expertise in the topic area. The aim is to foster interaction among major laboratories in the areas of RNA Biology and to enhance the education and development of junior investigators and fellows in NCI laboratories.

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