News and Events
Mutant RAS can shift other proteins’ positions inside cancer cells
Mutant RAS proteins help shuttle other proteins out of the cell nucleus and into the cytoplasm, where some can promote cancerous growth.
Read MoreCelebrating CCR Careers: David D. Roberts, Ph.D.
David D. Roberts, Ph.D., a biochemist who identified a new pathway that controls cell responses to stress and developed approaches to improve cancer therapy by shutting it down, announces his retirement from the NCI.
Read MoreClinical trial researching drug therapy for neuroendocrine neoplasms
A trial led by Jaydira Del Rivero, M.D., Associate Research Physician in the Developmental Therapeutics Branch, is studying a new drug for neuroendocrine neoplasms, a group of rare cancers.
Read MoreMaster regulators flip the switch on neuroblastoma’s developmental state
Waves of regulatory changes can transform self-renewing neuroblastoma cells into neurons.
Read MoreBenign nail condition linked to rare syndrome that greatly increases cancer risk
Researchers from CCR and the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) discovered the presence of a benign nail abnormality may lead to the diagnosis of a rare inherited disorder that increases the risk of developing cancerous tumors. The study suggests conducting nail evaluation of affected patients and at-risk family members.
Read MoreAligned Blog: Building Community: Celebrating AANHPI Heritage Month
The COVID-19 pandemic highlighted an alarming trend in anti-Asian hate across the United States. To celebrate Asian American, Native Hawaiian, and Pacific Islander (AANHPI) Heritage Month, Sonia A. Garcia, Ph.D., Scientific Diversity Program Manager in CCR's Office of Equity & Inclusion (OEI), highlights an NIH initiative created out of such adversity and shares the OEI's upcoming seminar series on advancing AANHPI folks into leadership positions.
Read MoreNew AI tool classifies brain tumors using images of tumor slides
A new artificial intelligence model has been found to be highly effective at identifying brain tumor subtypes — with 95% accuracy — simply by analyzing a standard pathology image of the tumor tissue.
Read MoreNew research identifies a protein essential to maintaining chromosomal stability
Researchers discovered how overproduction of a protein called CENP-A can lead to chromosomal abnormalities, which are found in many types of cancer.
Read MoreNew database of sarcoma cell line data will drive rare cancer research
CCR researchers have developed the largest publicly accessible sarcoma cell line database called Sarcoma CellMinerCDB. The tool merges previously available and new sarcoma cell line data that can be used to identify new therapeutic targets for these cancers.
Read MoreClinical trial researching combination therapy for solid tumors
A trial led by Steven A. Rosenberg, M.D., Ph.D., Chief of the Surgery Branch, is researching white blood cell gene therapy and vaccine therapy for certain metastatic cancers.
Read MoreThree CCR researchers elected to the National Academy of Sciences
Steven A. Rosenberg, M.D, Ph.D., Chief of the Surgery Branch, Giorgio Trinchieri, M.D., Chief of the Laboratory of Integrative Cancer Immunology, and Sandra L. Wolin, M.D., Ph.D., Chief of the RNA Biology Laboratory, were elected as 2024 members of the National Academy of Sciences in recognition of their distinguished and continuing achievements in original research. The Academy is committed to furthering science in America, and its members are outstanding contributors to the international scientific community.
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